IMS Research Cluster Events
2013 IMS Cluster Symposium May 9 - Click here for flyer
Immunology and Microbial Sciences (IMS) Training Program
The Immunology and Microbial Sciences (IMS) Training Program consists of a graduate curriculum that emphasizes research on microbes, the immune system, and the interface between the two fields. Students who participate in the training program conduct research that includes:
- Microbial physiology, microbial genetics, molecular biology, and the emerging fields of genomics and synthetic biology.
- Mechanisms of antimicrobial resistance and discovery of novel therapeutics
- Microbial pathogenesis, including bacteria, viruses, and parasites.
- Studies of microbial host-interactions, modulation of host cell biology, and development of disease or symbiosis
- Mechanisms by which microbes evade innate immune responses
- Genetics and development of a normal immune response and oral tolerance
- Immune response to infection including the generation and effects of the innate and adaptive systems
- The role of T cells, B-cells, mast cells, cytokines, and chemokines in host immunity
- Immunological diseases, including autoimmunity, inflammation, and allergy
The IMS program has a flexible curriculum that allows students to explore their interests in Microbiology and/or Immunology. During their first two years, students who participate in the IMS training program are required to take two entry-level courses in microbiology, virology, or immunology and one advanced topics course. In addition, students take part in topic specific training activities including journal clubs, research-in-progress meetings, and seminars. IMS students also attend quarterly meetings of the IMS program that will provide opportunities for students to share their research with peers who share their interest in Microbiology and Immunology.
The training faculty from both the DGP (Chicago campus) and IBiS (Evanston campus) who participate in the IMS program are listed below. Click on the name to see a research description.
- Karla Satchell, PhD (DGP) Associate Professor, Microbiology-Immunology, Feinberg School of Medicine
Bacterial and Viral Structure and Physiology
- Wayne Anderson, PhD (DGP) Crystallography of protein-protein interactions
- Jonathan Leis, Ph, (DGP) Mechanism of retrovirus replication; reverse transcription, integration, proteolytic processing, and assembly
- Joshua Leonard, PhD (IBiS) Engineering cellular systems and biomolecules for immunotherapy
- Aaron Packman, PhD (McCormick) Environmental transport processes
- Heather Pinkett, PhD (IBiS) Molecular basis for transport
- Erik Sontheimer, PhD (IBiS) Ribonucleoproteins and Eukaryotic Gene Expression
- Yun Wang, PhD (IBiS) Medical and environmental microbiology, aquatic geochemistry
Microbial Host-Interactions and Evasion of Innate Immunity
Bacteriology
- Nick Cianciotto, PhD (DGP) Pathogenesis of Legionella pneumophila, agent of Legionnaires Disease
- Alan Hauser, MD, PhD (DGP) Pseudomonas aeruginosa type III secretion and pathogenesis
- David Klumpp, PhD (DGP) Molecular Mechanisms of Bladder Inflammation and Pelvic Pain
- Wyndham Lathem, PhD (DGP) Host-pathogen interactions during Yersinia infections
- Mark Mandel, PhD (DGP) Host-microbiota specificity, communication, and evolution
- Karla Satchell, PhD (DGP) Vibrio cholerae RTX toxin and host-pathogen interactions
- Hank Seifert, PhD (DGP) Molecular mechanisms of Neisseria gonorrhoeae pathogenesis
Virology
- Michael Abecassis, MD (DGP) Cytomegalovirus latency and reactivation
- Eva Gottwein, PhD (DGP) Micro RNA in Herpes virus infections
- Thomas Hope, PhD (DGP) Viral Posttranscriptional Regulatory Elements and Cell Biology of HIV
- Curt Horvath, PhD (IBiS) Signal transduction and gene regulation in innate immune responses to cancer and viruses
- Laimonis Laimins, PhD (DGP) Human papillomaviruses and cervical cancer
- Robert Lamb, PhD, ScD (IBiS) Viral Glycoproteins, Ion Channels, and RNA-Binding Proteins
- Richard Longnecker, PhD (DGP) Epstein-Barr virus (EBV) and herpes simplex virus (HSV) entry, replication, and pathogenesis
- Greg Smith, PhD (DGP) Herpesvirus transport in the nervous system
Parasitology
- David Engman, MD, PhD (DGP) Molecular Pathogenesis of Infectious and Autoimmune Heart Diseases
Immunology And Immunological Diseases
- Melissa Brown, PhD (DGP) Expression of interleukin 4 (IL-4) and its role in normal and autoimmune responses
- Paul Bryce, PhD (DGP) Regulation of food allergy, asthma and allergic diseases by mast cells
- Joan Cook-Mills, PhD (DGP) Endothelial cell function during allergic disease
- Deyu Fang, PhD (DGP) Molecular networks in the regulation of immune response and autoimmunity
- Geoff Kansas, PhD (DGP) Molecular Biology of Leukocyte Adhesion and Migration
- William Karpus, PhD (DGP) Chemokines in Autoimmunity, Infectious Disease, and Lymphoma Metastasis
- Khashayarsh Khazaie, PhD (DGP) Immune Evasion and Inflammation in Cancer
- Douglas Kuperman, PhD (DGP) Mechanisms of asthma pathogenesis
- Nick Lu, PhD (DGP) Glucocorticoid receptor in asthma, inflammation, and cancer
- Xunrong Luo, MD, PhD (DGP) Tolerance mechanisms in autoimmune diabetes
- Stephen Miller, PhD (DGP) Immunoregulation of T Cell-Mediated Autoimmune and Virus Diseases
- William A. Muller, MD, PhD (DGP) Leukocyte-endothelial cell interactions in inflammation
- Thomas O'Halloran, PhD (IBiS) Metalloregulatory proteins; molecular mechanisms of metal-responsive gene expression
- Murali Prakriya, PhD (DGP) Intracellular Calcium Signaling
- Harris Perlman, PhD (DGP) The role of cell cycle and apoptosis regulators in autoimmune disease
- Hyewon Phee, PhD (DGP) Signal transduction pathways in T cell migration, activation and autoimmunity
- Richard Pope, MD (DGP) Cellular immune mechanisms in rheumatoid arthritis
- Robert Schleimer, PhD (DGP) Glucocorticoids in allergic diseases
- Christian Stehlik, PhD (DGP) Molecular mechanisms of inflammatory and infectious disease
- Edward Thorp, PhD (DGP) Inflammation resolution and repair in cardiovascular disease
- Praveen Thumbikat, PhD (DGP) Microbial and autoimmune mediated inflammation and immune mechanisms in prostate disease
- Chyung-Ru Wang, PhD (DGP) Role of MHC class Ib molecules: H2-M3 and CD1
- Bin Zhang, PhD (DGP) Cancer immunotherapy by antitumor T cells
- Liang Zhou, PhD (DGP) Th17 and Treg cell differentiation: molecular mechanisms and function in autoimmunity and infection

